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Trial concept calculated: phase of a clinical trial as per ICH E8(R1).

Usage

f.trialPhase(df = NULL)

Arguments

df

data frame such as from dbGetFieldsIntoDf. If `NULL`, prints fields needed in `df` for calculating this trial concept, which can be used with dbGetFieldsIntoDf.

Value

data frame with columns `_id` and `.trialPhase`, which is an ordered factor with levels `phase 1`, `phase 1+2`, `phase 2`, `phase 2+3`, `phase 2+4`, `phase 3`, `phase 3+4`, `phase 1+2+3`, `phase 4`, `phase 1+2+3+4`.

Examples

# fields needed
f.trialPhase()
#> $euctr
#> [1] "e71_human_pharmacology_phase_i"        
#> [2] "e72_therapeutic_exploratory_phase_ii"  
#> [3] "e73_therapeutic_confirmatory_phase_iii"
#> [4] "e74_therapeutic_use_phase_iv"          
#> 
#> $ctgov
#> [1] "phase"
#> 
#> $ctgov2
#> [1] "protocolSection.designModule.phases"
#> 
#> $isrctn
#> [1] "interventions.intervention.phase"
#> 
#> $ctis
#> [1] "authorizedPartI.trialDetails.trialInformation.trialCategory.trialPhase"                      
#> [2] "authorizedApplication.authorizedPartI.trialDetails.trialInformation.trialCategory.trialPhase"
#> 

# apply trial concept when creating data frame
dbc <- nodbi::src_sqlite(
  dbname = system.file("extdata", "demo.sqlite", package = "ctrdata"),
  collection = "my_trials", flags = RSQLite::SQLITE_RO)
trialsDf <- dbGetFieldsIntoDf(
  calculate = "f.trialPhase",
  con = dbc)
#> Querying database (9 fields)...
trialsDf
#>                  _id .trialPhase
#> 1           12949496     phase 3
#> 2           13281214     phase 3
#> 3           17473621     phase 3
#> 4  2012-003632-23-CZ     phase 2
#> 5  2012-003632-23-SE   phase 2+3
#> 6  2014-002606-20-PT     phase 3
#> 7  2014-003556-31-GB     phase 2
#> 8  2014-003556-31-SE     phase 2
#> 9  2022-500244-37-00     phase 2
#> 10 2022-501142-30-00     phase 4
#> 11 2023-505613-24-00     phase 2
#> 12 2023-508143-51-01     phase 4
#> 13 2024-510663-34-00     phase 2
#> 14          20343063     phase 3
#> 15          61070850     phase 3
#> 16          76463425     phase 3
#> 17          80181452     phase 3
#> 18          88261002     phase 3
#> 19       NCT00617929     phase 2
#> 20       NCT01125800   phase 1+2
#> 21       NCT01483820   phase 1+2
#> 22       NCT01505608   phase 1+2
#> 23       NCT01592045   phase 1+2
#> 24       NCT02620761   phase 2+3
#> 25       NCT03280147     phase 3
#> 26       NCT03325439     phase 3
#> 27       NCT03431558     phase 3
#> 28       NCT03876704     phase 3
#> 29       NCT04001712     phase 3
#> 30       NCT04041765     phase 3
#> 31       NCT05969327     phase 3